The Role of Polymorphism of Interleukin 10 and 12 in Hepatitis C

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Verlag: LAP Lambert Academic Publishing
Autor: Omnia Aly
Artikel-Nr.: KNV76893511
ISBN: 9786139457502

Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level... mehr

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Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. It was aimed to detect single nucleotide polymorphisms (SNPs) of the IL-I0 promoter region at nucleotides -1082 &-592 and IL-12 promotor region at nucleotide -1188., also we measured Il-10 and IL12 protein level in the serum of chronic liver diseased patients under treatment with peg IFN- plus ribavirin and compare the results with non infected subjects.

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