In Part II of this special issue of Nursing Clinics of North America, Dr. Krau is serving as Guest Editor again to provide information on complementary and alternative medicine with specific focus on herbal supplements and vitamins. Distinguished authors have contributed clinical reviews devoted to the following topics: Precautions when using Herbal Medications and Supplements; Vitamin B6 and its role in Women's Health; Fat Soluble Vitamins; Vitamin D: Vitamin or Hormone; Enhancing Cognitive Function with Herbal Supplements; Herbal Medications Used in Women's Health; Herbal Medication to Enhance or Modulate Viral Infections; Herbal Medications used to treat fevers; Traditional and Current Use of Ginseng; Herbal Medications Used to ameliorate cardiac conditions; Cannabis, Marijuana, and CBD oil; and Highs, Lows, & Health Hazards of Herbology-A Review of Herbal Medications with Psychotropic Effects. Knowledge of this information is not easy to find in the nursing literature, and Dr. Krau believes readers will come away with valuable information on managing patients who use complementary and alternative herbal supplements and vitamins.