Together with Consulting Editor Dr. Bonita Stanton, Dr. Elizabeth Secord has put together a comprehensive issue that discusses the updates in pediatric immunology and allergy. Expert authors have contributed clinical review articles on the following topics: Humoral Immune deficiency in childhood; Neutrophil deficiencies; Newborn screening for severe combined immune deficiency (SCID); New treatments for asthma; New insights and treatments in Atopic Dermatitis; Food allergy avoidance and treatments; Eosinophilic Esophagitis; Inner City Asthma; Allergic rhinitis; Anaphylaxis in children and adolescents; Biologic therapy induced immune deficiency; Drug Allergies and Sensitivities in children; and Secondary immune deficiency. Readers will come away with the information they need to improve outcomes in pediatric patients with immunologic and allergic conditions.