This book is a brief review of endodontic instruments which a clinician use in his or her practice. By reading this book a clinician gets good knowledge of endodontic instruments. Cleaning and shaping are performed by a combination of mechanical removal of the infected and non-infected root canal tissue, as well as some dentine from the root canal wall, and chemical disinfection by removal of bacteria and their products from within the root canal spaceClinical evidence demonstrates that root canal systems can be cleaned and shaped in three dimensions and can be obturated in three dimensions with a high degree of predictability, approaching 100% success. Three major elements determine the predictability of successful endodontics. The first is knowledge, the second is skill, and the third is desire. The endodontic disease process has been identified, and treatment has been developed. Discipline and skills need to be developed, but the critical factor.