This textbook combines research findings with practical relevance for physiotherapists, sports scientists, and orthopedists in the management of acute and chronic pain. Insights from pain research provide a deeper understanding of the neurobiological processes involved in pain and are applied to practical use. Contents include: the history of pain from ancient times to the present, neurobiology of nociception and pain, cortical-neuronal and biochemical correlates of pain perception and neuroplasticity, the discussion of postural-structural-biomechanical factors in relation to pain development, practical assessment strategies with questionnaires and documentation, as well as the most effective therapeutic methods, case-specific exercise recommendations for chronic back, neck, shoulder, and knee pain. This textbook deepens your knowledge of the symptom of pain and helps you better understand your patients' complaints, which is a fundamental prerequisite for optimal education and treatment.